Collapsible loess is prone to self weight collapse after soaking. The strength of loess will be greatly reduced, and it will threaten the safe operation of buried pipelines along the way. In order to study the stability of buried pipelines in collapsible loess regions, the displacements, stresses and strains of different pipe outer diameters and wall thicknesses during collapsing were analyzed based on the finite element method. The limit length that the buried pipeline could withstand in the loess disaster under certain conditions was obtained by the eigenvalue buckling theory. The results show that: increasing the outer diameter and wall thickness of the pipeline and reducing the buried depth of the pipeline in the loess can effectively reduce the displacement of the pipeline in the collapsible loess; and increasing the outer diameter and wall thickness of the pipeline can also effectively avoid the phenomenon that the local stress of the pipeline is too high; the maximum stress and strain of the pipeline occur at the center of the collapsing zone and the fixed ends on both sides; according to the buckling eigenvalue theory, the ultimate length of the collapsible area of the pipeline is about 65 m when the soil mass has self weight collapsible, and increasing the outer diameter and wall thickness of the pipeline can enhance the buckling resistance of buried pipelines when self weight collapse after soaking.